Adrenal insufficiency precipitated by Graves' hyperthyroidism in a patient on megestrol acetate treatment
نویسندگان
چکیده
منابع مشابه
Adrenal insufficiency in a haemodialysis patient
Adrenal insufficiency in a haemodialysis patient Sir, Abnormalities in the hypothalamic–pituitary– adrenocortical (HPA) axis do not usually lead to severe adrenal insufficiency in haemodialysis (HD) patients. However, drug administration may trigger a paradigm shift. A 67-year-old man receiving HD therapy for 4 years was admitted to our hospital due to a traumatic fracture of the right rib. Tre...
متن کاملMegestrol acetate for the treatment of anorexia-cachexia syndrome.
BACKGROUND Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer-associated anorexia. In 1993 MA was approved by the USA's Federal Drug Administration for the treatment of anorexia, cachexia, or unexplained weight loss in patients with AIDS. The mechanism by which MA increases appetite is unknown, and its effectiveness for anorexia and cachexia in neoplas...
متن کاملDevelopment of Graves' hyperthyroidism caused an adrenal crisis in a patient with previously unrecognized non-classical 21-hydroxylase deficiency.
A 75-year-old woman was found to be unconscious in hospital. She was febrile with a temperature of 38.4 degrees C. She had hypotension (blood pressure 80/40 mmHg) with serum Na 132 mEq/L and K 5.7 mEq/L (serum Na/K = 23.2), and serum cortisol 0.91 microg/dL, indicative of adrenal failure. She was admitted for the treatment of Graves' hyperthyroidism, and was found to be unconscious in hospital....
متن کاملThyroidectomy for Graves’ hyperthyroidism
Hyperthyroidism in Graves’ disease can be managed with administration of radioiodine or pharmacologically with thionamides or surgically treated with subtotal or total thyroidectomy. The choice of therapy will depend on patient age and preferences, thyroid size, disease severity, presence of ophthalmopathy, and local resources and practices. Treatment policies vary considerably within and betwe...
متن کاملMegestrol acetate in cachexia and anorexia
The aim is to review major clinical trials that have used megestrol acetate (MA) in the treatment of cachexia across several disease states. A review of general usage and potential side-effects are discussed. A theory that the newly approved nanocrystal formation of MA can better deliver this potent medication for treatment will also be reviewed.
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ژورنال
عنوان ژورنال: Endocrine Abstracts
سال: 2016
ISSN: 1479-6848
DOI: 10.1530/endoabs.41.ep253